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Hyperbaric Oxygen Therapy
Severe Burns
The type of burn and its severity depends on how many layers of the skin are damaged. The skin is made up of of three layers, including the epidermis, dermis, and subcutaneous tissue. HBOT provides the body and the damaged tissue with high levels of oxygen. This helps minimize swelling, preserve damaged tissue, and reduce the risk of tissue death and scarring, as well promote white blood cells - which helps fight off infection and encourage wound closure.
HBOT helps decrease the chance of severe complications by up to 80%.
Studies on
Severe Burns and HBOT
Effects of hyperbaric oxygen therapy on the healing of thermal burns and its relationship with ICAM-1: A case-control study
Oley MH, Oley MC, Aling DMR, Kalangi JA, Islam AA, Hatta M, Patellongi IJ, Josh F, Faruk M. Effects of hyperbaric oxygen therapy on the healing of thermal burns and its relationship with ICAM-1: A case-control study. Ann Med Surg (Lond). 2020 Dec 25;61:104-109. doi: 10.1016/j.amsu.2020.12.025. PMID: 33437471; PMCID: PMC7785995.
ABSTRACT
Background: The damaging effects of thermal burns need to be managed holistically in order to create a suitable environment for wound healing. The purpose of our study was to investigate the effects of hyperbaric oxygen therapy (HBOT) on the healing of thermal burns and its relationship with intercellular adhesion molecule 1 (ICAM-1).
Conclusion: HBOT can reduce thermal wound complications, length of stay in hospitals due to thermal burns, ICAM-1 mRNA gene expression, and ICAM-1 serum level.
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Bactericidal effect of hyperbaric oxygen therapy in burn injuries
Oley MH, Oley MC, Wewengkang LAJW, Kepel BJ, Langi FLFG, Setiadi T, Aling DMR, Gunawan DF, Tulong MT, Faruk M. Bactericidal effect of hyperbaric oxygen therapy in burn injuries. Ann Med Surg (Lond). 2022 Jan 31;74:103314. doi: 10.1016/j.amsu.2022.103314. PMID: 35145678; PMCID: PMC8819012.
Abstract
Introduction
Burn injuries are frequently encountered in emergency cases and often become the port of entry for pathogens. More than 450,000 burn injuries occur annually causing nearly 3,400 deaths in the United States. The prevalence of burn injury in Indonesia is 0.7% in 2013. More than half of these According to several studies on the use of patients were treated for bacterial infections, some of which were resistant to certain antibiotics. Using hyperbaric oxygen therapy (HBOT) to treat burns has several positive effects including managing bacterial infections, as well as accelerating the wound healing process. Therefore, this study aims to prove the effectiveness of HBOT in inhibiting bacterial growth.
Conclusion: HBOT administration can significantly reduce bacterial growth in burn injuries.